Research in Pharmacy and Health Sciences

ISSN: 2455 5258
An International Peer Review Journal

Volume 3, Issue 2: April 2017 – June 2017

1. Evaluation of Antiasthmatic Activity of Murraya Koenigii L. Leaves
Jitendra Singh Rathore*, Umesh Gilhotra
The present investigation was designed to evaluate the anti-asthmatic activity of ethanolic extract of Murraya Koenigii Leaves in experimental animals. Murraya Koenigii Leaves was evaluated for anti-histaminic activity using isolated Guinea pig tracheal chain preparation, histamine induced Bronchoconstriction in Guinea pig and milk induced leucocytosis in mice. Ethanolic extract of Murraya Koenigii Leaves oral dose 400mg/kg body weight significantly inhibited dose dependent contraction of Guinea pig tracheal chain produced by histamine and also showed significant protection by prolonging PreConvulsion Dyspnoea time (PCT) in guinea pigs. Murraya Koenigii Leaves was evaluated by milk induced leucocytosis in mice showed significant decreased of total leukocyte count.  Thus, Murraya Koenigii Leaves showed anti-allergic activity against histamine hence possesses potential role in the treatment of asthma.

2. Hidden Potential of Natural Herb Carissa Carandas (Karonda)
Reshu Virmani*, Tarun Virmani, Charan Singh, Geeta Sorout, Jyoti Gupta
Carissa carandas (F. Apocynaceae) is an important fruit commonly known as Karonda ‘Christ’s thorn’ which grows wild in bushes. Carissa carandas is a useful food and medicinal plant of India, found to be widely distributed throughout subtropical and topical regions. The plant has been used as a traditional medicinal plant over thousands of years in the Ayurvedic, Unani, and Homoeopathic system of medicine. The major bioactive constituents, which impart medicinal value to the herb, are alkaloids, flavonoids, saponins and large amounts of cardiac glycosides, triterpenoids, phenolic compounds and tannins. Roots were reported to contain volatile principles including 2-acetyl phenol, lignan, carinol, sesquiterpenes (carissone, carindone), lupeol, β-sitosterol, 16β-hydroxybetulinic acid, α-amyrin, β-sitosterol glycoside, and des-N-methylnoracronycine, whereas leaves were reported to contain triterpenoid constitutes as well as tannins. While, fruits have been reported to contain carisol, epimer of α-amyrin, linalool, β-caryophyllene, carissone, carissic acid, carindone, ursolic acid, carinol, ascorbic acid, lupeol, and β-sitosterol. Traditionally the plant has been used in the treatment of scabies, intestinal worms, pruritus, biliousness and also used as antiscorbutic, anthelmintic. The notable biological activities reported are analgesic, anti inflammatory, anti pyretic, cardiotonic and histamine releasing. This review has been written to presents a detailed survey of the literature on phytochemistry, traditional and biologically evaluated medicinal uses of C. carandas to promote safe and effective herbal treatments to cure a number of diseases.

3. In-patient and Out-patient Pharmacist Intervention in the Management of Diabetes Mellitus Conditions in Dubai, United Arab Emirates: A Qualitative Approach  
Ibrahim Khalid Rayes*, Omar Saad Saleh Abrika
There is a growing body of literature showing the importance of pharmacists’ involvement in the management of Diabetes Mellitus (DM) conditions. This study tried to explore the extent to which pharmacists in Dubai, United Arab Emirates intervene in the management and control of diabetic patients within different healthcare settings by using a qualitative approach method. Based on the sample pooled, our key findings pointed to the lack of pharmacists’ intervention in designing or altering DM drug therapy. In addition, hospital pharmacists in Dubai are not actively involved in the management and control of DM conditions. The only positive role of pharmacists were found in the primary healthcare setting where community pharmacists are consulted regularly on sudden or urgent complications related to DM conditions.

4. Epidermodysplasia Verruciformis: A Dreadful Disease
Tarun Virmani*, Virmani Reshu, Tanwar Rohit, Chhabra Vaishnavi
Epidermodysplasia Verruciformis or tree man illness disease is extremely dreadful, rare and genetic hereditary skin disorder. Disease usually begins in infancy or early childhood, with the development of various types of flat, wart like lesions and confluent plaques on the skin. Various types of treatment were reported by various researchers for the treatment of Tree man illness disease, but very few were on the contra indicatory part.  However, if the epidermodysplasia verruciformis has already progressed into a carcinoma that is invasive in nature, then a surgical excision may be necessary to prevent further problems.

5. Nutritional Status and Utilization of Anganwadi Services: An Epidemiological Comparative Study Medak District, Telangana, India
Gangadhar Rao kalapala, Shamanna BR, B Ravi Zechariah
Background: Malnutrition is the widely prevalent problem in India as well as other developing countries; India has one of the astonishing magnitudes according to the national family health survey.  The Integrated Child Development Services (ICDS) programme is a globally recognized community based early child care programme, which addresses the basic interrelated needs of young children, expectant and nursing mothers and adolescent girls across the life cycle, in a holistic manner. ICDS in India is a response the challenge of breaking a vicious cycle of mal-nutrition, impaired development, morbidity and mortality in young children, working in convergence with other flagship programmes. Material and methods: It is an observational cross sectional study design sampling was obtained through the simple random sampling .The sample size consists of 100 anganwadi children  Results: The present study the findings have shown that Mean age of the children= 43.27 months    Males 50% and Females 50% ,Average age of weaning=9.89=10 months,  per cent of children attending anganwadi centre =97.6% ,Children attending anganwadi centres regularly=53% Children attending anganwadi centre irregular=29% Children attending anganwadi less than two days in a week=18%. Conclusion: The prevalence of malnutrition in males and females are comparatively higher as 48.8% and 49.4, despite many programs and efforts put down by the government the malnutrition rates are still prevail high in the country .the programs were beneficial to only certain class of people.

6. A study on the Relationship of the weight pattern with the socioeconomic status among adolescents school going children in an Indian Metropolitan City
Samar Hossain*, Sharma Priyanka, Talib Hossain, Surendra Mohan Mathur
Objective: The last two decades have witnessed an increase in health care costs due to obesity and related issues among children and adolescents. Childhood obesity is a global phenomenon affecting all socio-economic groups, irrespective of age, sex or ethnicity. The study was done to find the the prevalence of obesity and overweight and their association with socioeconomic status (SES) and the risk factors. Materials and Methods: School based cross sectional study carried out over a period of 4 months in three schools of East Delhi. The study was carried out in 629 school children of 10–18 years of age and belonging to different socioeconomic statuses in schools in East Delhi. The obesity and overweight were considered using an updated body mass index reference. A pre-tested questionnaire was used to determine the Socio-economic status and life style factors. Results: The prevalence of overweight among children was higher in middle socioeconomic status groups as compared to high socioeconomic class in both boys and girls whereas the prevalence of obesity was higher in high Socio economic status group as compared to middle socioeconomic group. The prevalence of obesity as well as overweight in low SES group was the lowest as compared to other group. Conclusion: The findings of this study suggest that the prevalence of overweight and obesity varies remarkably with different socioeconomic development levels.


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