Molecular Docking an Enchanted Way in The Discovery of Novel Molecule in Designing Drug: A Focused Review

Current review paper revolves around the method of molecular docking. It involves the basics of docking studies. It also focused on the biological and pharmaceutical significance of the molecular docking, considerable efforts have been directed towards improving the methods used to predict docking. There is a general concept about molecular docking is lock and key in which the finding is the correct relative orientation of the key which can best be fitted into the lock and then the lock can be open easily. How the accurate structure can be designed and what are the correct activities are predicted are the main two aims of the docking studies are preferred in the given studies and some examples are also added within the review for the evidence which supports the importance of docking studies. Keywords: Molecular docking, Affinity, Scoring function, Protein binding, Ligand.